Table 3.
Insecticidal activities of selected cupiennins, CsTx-16 variants, neurotoxins CsTx-1, CsTx-9, and CsTx-13, and cyto-insectotoxin CIT1a. Different concentrations of peptides were dissolved in 0.1 M ammonium acetate, pH 6.1, and 0.05 µl was injected into Drosophila flies. The lethal dose (LD50, pmol/mg fly), where 50% of the flies die after 24 h, was calculated with PRISM Vers. 6.07. * Data are from14, ** from25, *** from18, using flesh flies.
| Peptide | LD50 | 95% Confidence Intervals |
|---|---|---|
| (pmol/mg fly) | ||
| Cu 1a* | 5.9 | 4.2–8.3 |
| Cu 1b* | 4.7 | 3.9–5.7 |
| Cu 1d* | 6.4 | 5.4–7.6 |
| Cu 3a | 18.7 | 17.11–20.4 |
| Cu 3e | 38.5 | 34.2–43.3 |
| Cu 3d | 12.7 | 11.3–14.1 |
| Cu 4a | 12.4 | 11.0–14.1 |
| Cu 6a | 78.0 | 70.3–86.6 |
| Cu 6b | 39.5 | 35.6–43.9 |
| Cu 6d | 23.2 | 21.4–25.2 |
| Cu 7b | 438.1 | 423.6–453.0 |
| Cu 8 | 159.7 | 154.7–164.8 |
| CsTx-16a1b1 | 63.5 | 58.1–69.3 |
| CsTx-16c1d1 | 53.6 | 49.1–58.5 |
| CsTx-1** | 0.53 | 0.515–0.555 |
| CsTx-9** | 45.54 | 43.30–47.78 |
| CsTx-13** | 111.2 | 105.5–116.9 |
| CIT1a*** | ~ 0.6 |