Table 2.

Receiver operating characteristics area under the curve analysis in all patients at 5, 10, and 15 min before a hypotensive event defined by mean arterial pressure (MAP) < 65 mmHg sustained for a minute

Time	AUC [95% Conf]	Sensitivity	Specificity	Threshold
Combined (N = 305)
5 min	0.93 [0.91,0.95]	0.86 [0.82,0.89]	0.86 [0.82,0.89]	30
10 min	0.90 [0.87,0.93]	0.83 [0.79,0.86]	0.83 [0.79,0.86]	28
15 min	0.84 [0.79,0.88]	0.75 [0.71,0.80]	0.75 [0.71,0.80]	22
Blinded arm (N = 150)
5 min	0.94 [0.90,0.96]	0.86 [0.82,0.91]	0.87 [0.82,0.91]	30
10 min	0.93 [0.88,0.96]	0.87 [0.81,0.92]	0.87 [0.81,0.91]	28
15 min	0.83 [0.75,0.89]	0.75 [0.68,0.82]	0.75 [0.68,0.81]	22
Unblinded arm (N = 155)
5 min	0.93 [0.91,0.95]	0.86 [0.82,0.89]	0.86 [0.82,0.89]	31
10 min	0.90 [0.87,0.93]	0.83 [0.79,0.86]	0.83 [0.79,0.86]	31
15 min	0.84 [0.79,0.88]	0.75 [0.71,0.80]	0.75 [0.71,0.80]	22

Sensitivity and specificity are given at the optimal threshold for HPI