Table 2.

Logistic regressions for liver fibrosis (LS ≥ 2.9 kPa)

		Univariate		Multivariable
		OR (95% CI)	P	AOR (95% CI)	P
Age	Years	1.04 (1.01–1.07)	0.021	1.05 (1.02–1.09)	0.005
Sex	M vs. F	1.20 (0.78–1.85)	0.413	1.01 (0.61–1.67)	0.977
Race/ethnicity	Black non-Hispanic	Reference
	White non-Hispanic	1.30 (0.64–2.64)	0.397	1.06 (0.48–2.34)	0.878
	Hispanic	0.92 (0.56–1.51)	0.448	0.79 (0.44–1.41)	0.415
Income	Per $1,000	0.99 (0.97–1.01)	0.243	0.99 (0.97–1.01)	0.434
BMI	kg/m2	0.97 (0.94–1.01)	0.145	0.99 (0.95–1.04)	0.769
Hyperglycemia		3.35 (1.81–6.17)	0.0001	3.80 (1.87–7.72)	0.0002
Liver Steatosis	% (continuous)	1.02 (0.97–1.07)	0.498
	>5% (binary)	1.22 (0.70–2.13)	0.483
HIVa	Suppressed	1.51 (0.96–2.38)	0.074	2.21 (1.30–3.76)	0.004
	Not suppressed	2.11 (1.01–4.43)	0.047	3.70 (1.51–9.03)	0.004
HCVb	Undetectable	2.57 (1.37–4.83)	0.003	3.17 (1.66–6.06)	0.001
	Viremicc	7.30 (4.18–12.73)	<0.0001	9.05 (4.94–16.6)	<.0001
Alcohol	AUDIT≥8	1.17 (0.72–1.91)	0.519
	AUDIT≥13/15	1.48 (0.79–2.78)	0.219	2.11 (0.90–4.91)	0.085
	History of problems	1.14 (0.73–1.77)	0.560	0.84 (0.46–1.55)	0.577
Cigarette Smoking		0.98 (0.64–1.50)	0.919
Cannabis		0.94 (0.86–1.52)	0.810
Cocaine		0.85 (0.55–1.31)	0.466
Opioids	Prescription	0.92 (0.48–1.75)	0.788
	Heroin	2.22 (1.10–4.44)	0.025	2.77 (1.18–6.50)	0.019
Polysubstance	# of substances	0.90 (0.59–1.38)	0.639	0.90 (0.71–1.14)	0.387

Bold values are those that are statistically significant at p < 0.05.

^aReference is HIV uninfected

^bReference is HCV seronegative

^cViremic HCV-seropositive had 2.84 (95% CI 1.38–5.84) time the odds for liver fibrosis than those with undetectable HCV viral load; P=0.005. In multivariable regression, viremic HCV-seropositive participants had 2.88 (95% CI 1.31–6.32) times the odds for liver fibrosis than those with undetectable HCV viral load; P=0.008