Table 1:
Cohort demographics, overall and broken down before and after the informal Oct 2010 dosing consensus. P values are for difference between the pre- and post-Oct 2010 groups.
| Overall | pre-Oct 2010 | post-Oct 2010 | P value (pre vs. post) | |
|---|---|---|---|---|
| n | 2,328 | 525 | 1,803 | |
| Sex = Male (%) | 983 ( 42.2) | 207 ( 39.4) | 776 ( 43.0) | 0.14 (Χ2) |
| Age (yrs; mean (SD)) | 45.38 (15.98) | 42.01 (13.40) | 46.37 (16.54) | <0.0001 (t-test) |
| Charge (mC; mean (SD)) | 21.82 (21.61) | 18.73 (8.99) | 22.72 (24.00) | 0.0002 (t-test) |
| Seizure Duration (sec; mean (SD)) | 76.19 (36.65) | 66.57 (30.49) | 79.00 (37.82) | <0.0001 (t-test) |
| Anesthesia Type (%) | ||||
| Ketamine | 1 ( 0.0) | 0 (0.0) | 1 ( 0.1) | |
| Etomidate | 3 ( 0.1) | 3 ( 0.6) | 0 (0.0) | |
| Methohexital | 2,250 ( 99.5) | 510 ( 98.8) | 1,740 ( 99.7) | |
| Propofol | 6 ( 0.3) | 3 ( 0.6) | 3 ( 0.2) | |
| Charge (%) | ||||
| <19.2 mC | 166 ( 7.1) | 148 ( 28.2) | 18 ( 1.0) | |
| 19.2 mC | 1,922 ( 82.6) | 311 ( 59.2) | 1,611 ( 89.4) | |
| >19.2 mC | 240 ( 10.3) | 66 ( 12.6) | 174 ( 9.7) | |
| Age (%) | ||||
| <35 | 694 ( 29.8) | 169 ( 32.2) | 525 ( 29.1) | |
| 35–50 | 685 ( 29.4) | 195 ( 37.1) | 490 ( 27.2) | |
| >50 | 949 ( 40.8) | 161 ( 30.7) | 788 ( 43.7) |