. Author manuscript; available in PMC: 2022 Nov 1.

Published in final edited form as: J Am Acad Dermatol. 2020 Aug 18;85(5):1253–1258. doi: 10.1016/j.jaad.2020.08.047

Table 3.

Regression Results of Secondary Risk Factors on Cutaneous Changes

	Age	HSCT^*	Voriconazole Use	GvHD^*	Radiation

	Poisson Regression: Incidence Rate Ratio (95% CI) P-value

Cafe-au-lait macules	1.002 (0.601, 1.673) 0.759	1.093 (0.766, 1.560) 0.623	1.224 (0.867, 1.728) 0.250	0.986 (0.591, 1.646) 0.957	0.909 (0.655, 1.261) 0.988
Hypopigmented macules	1.002 (0.970, 1.035) 0.889	1.789 (0.695, 4.606) 0.228	1.009 (0.491, 2.071) 0.981	1.275 (0.443, 3.670) 0.653	1.039 (0.243, 1.835) 0.995

	Logistic Regression: Odds Ratio (95% CI) P-value

Sun-exposed freckling	0.924 (0.837, 1.000) 0.080	2.939 (0.701, 20.101) 0.185	15.250 (3.428, 107.947) 0.001	0.581 (0.030, 3.504) 0.621	1.707 (0.478, 6939) 0.421
Skin-fold freckle-like macules	1.067 (1.009, 1.111) 0.023	1.778 (0.644, 5.457) 0.284	0.420 (0.091, 1.431) 0.203	1.311 (0.329, 4.461) 0.677	1.853 (0.703, 5.164) 0.221

HSCT = Hematopoietic stem cell transplantation; GvHD = Graft-versus-host-disease

HSCT, Voriconazole use, GvHD, Radiation = secondary risk factors