Table 4.
Univariate | Multivariate | |||||
---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | |
Gender (reference: male) | 0.76 | 0.5–1.14 | 0.178 | – | – | – |
Admission SOFA Score (per 1 pt increment) | 1.12 | 1.06–1.18 | < 0.001 | – | – | – |
Admission SAPS2 Score (per 1 pt increment) | 1.03 | 1.02–1.04 | < 0.001 | 1.02 | 1.00–1.03 | 0.044 |
Primary ICU diagnosis (reference septic shock) | ||||||
Non-septic shock | 1.01 | 0.38–2.64 | 0.989 | 0.51 | 0.16–1.56 | 0.237 |
Resuscitated cardiac arrest | 2.71 | 1.57–4.68 | < 0.001 | 2.29 | 1.17–4.48 | 0.015 |
Acute on chronic respiratory failure | 0.58 | 0.26–1.30 | 0.187 | 0.95 | 0.36–2.53 | 0.921 |
Acute respiratory failure | 0.46 | 0.24–0.87 | 0.017 | 0.55 | 0.25–1.21 | 0.139 |
Neurological disorder | 0.96 | 0.51–1.83 | 0.912 | 1.14 | 0.49–2.64 | 0.758 |
Post-surgery | 0.25 | 0.06–1.04 | 0.057 | 0.34 | 0.07–1.57 | 0.168 |
Other | 0.56 | 0.23–1.36 | 0.200 | 0.75 | 0.26–2.12 | 0.582 |
Invasive mechanical ventilation | 2.56 | 1.11–5.89 | 0.027 | 1.48 | 0.52–4.21 | 0.466 |
RRT requirement | 1.52 | 1.00–2.31 | 0.051 | 1.53 | 0.86–2.71 | 0.147 |
Vasopressor requirement | 1.34 | 0.87–2.08 | 0.188 | 1.07 | 0.60–1.90 | 0.814 |
CIRS for geriatrics (per 1 pt increment) | 0.99 | 0.94–1.03 | 0.560 | – | – | – |
CIRS for geriatrics < 8 | 0.76 | 0.52–1.12 | 0.171 | – | – | – |
Residential living (reference: chronic care facility) | ||||||
Supervised residence setting | 0.25 | 0.05–1.11 | 0.068 | 0.15 | 0.03–0.84 | 0.030 |
At home | 0.25 | 0.08–0.82 | 0.021 | 0.17 | 0.05–0.62 | 0.007 |
IADL (per 1 pt increment) | 0.99 | 0.84–1.17 | 0.905 | – | – | – |
IADL ≥ 4 | 0.99 | 0.68–1.47 | 0.998 | – | – | – |
Katz-ADL (per 1 pt increment) | 0.97 | 0.83–1.13 | 0.705 | – | – | – |
Katz-ADL ≥ 5 | 0.88 | 0.54–1.42 | 0.598 | – | – | – |
History of fall (reference: no) | ||||||
Yes | 1.05 | 0.71–1.56 | 0.789 | – | – | – |
Unknown | 0.83 | 0.11–6.0 | 0.855 | – | – | – |
Cognitive impairment | 0.96 | 0.63–1.48 | 0.872 | – | – | – |
Perceived quality of life (unhappy, very unhappy) | 1.85 | 1.20–2.87 | 0.006 | 1.95 | 1.12–3.41 | 0.018 |
Chronic pain (reference: no) | ||||||
Mild | 1.08 | 0.62–1.89 | 0.781 | – | – | – |
Moderate | 1.31 | 0.79–2.18 | 0.295 | – | – | – |
Severe | 1.01 | 0.57–1.77 | 0.987 | – | – | – |
Presence of anxiety: yes | 1.36 | 0.90–2.05 | 0.140 | 1.64 | 1.00–2.69 | 0.051 |
Presence of depressive symptoms | 1.17 | 0.79–1.74 | 0.424 | – | – | – |
Mini-Zarit (per 1 pt increment) | 1.03 | 0.91–1.17 | 0.641 | – | – | – |
< 2 | 1.00 | 0.65–1.52 | 0.990 | – | – | – |
Frailty (reference: robust) | ||||||
Prefrail | 1.69 | 1.01–2.82 | 0.045 | 1.59 | 0.90–2.80 | 0.112 |
Frail | 1.59 | 0.93–2.71 | 0.092 | 1.03 | 0.50–2.14 | 0.933 |
ADL, Activity of daily living, CIRS for geriatrics, Cumulative Illness Rating Scale for Geriatrics, IADL, Instrumental Activity of Daily Living, ICU, intensive care unit, RRT, renal replacement therapy, SAPS, Simplified Acute Physiology Score, SOFA, Sequential Organ Failure Assessment
CIRS for geriatrics under 8 is suggestive of few comorbidities