Table 3.
Features of different histopathological types of MPO-ANCA-GN.
| Focal (n = 32) | Mixed (n = 26) | Crescentic (n = 29) | Sclerotic (n = 66625) | p | |
|---|---|---|---|---|---|
| Total glomeruli | 18.9 ± 12.3 | 17.6 ± 8.6 | 17.3 ± 7.0 | 17.0 (11.5, 26.5) | 0.877 |
| Normal glomeruli (%) | 66.1 (50.0, 76.3) | 29.8 ± 12.9 a | 22.5 ± 11.7 a | 11.6 (5.6, 21.7) a , b | <0.001 |
| Global sclerotic glomeruli (%) | 4.2 (0, 12.2) | 23.3 ± 14.4a | 11.8 (0, 27.5) | 74.1 ± 12.8a a , b | <0.001 |
| Cellular crescents (%) | 9.6 (0, 23.1) | 22.8 ± 15.0 | 58.3 (55.1, 64.7) a , b | 16.7 (7.3, 30.2) c | <0.001 |
| Acute tubulointerstitial lesions score | 2.0 (1.0, 3.0) | 3.0 (2.0, 3.0) a | 3.0 (3.0, 3.0) a | 3.0 (3.0, 3.0) a | <0.001 |
| Chronic tubulointerstitial lesions score | 1.0 (1.0, 1.0) | 1.0 (1.0, 2.0) | 1.0 (1.0, 2.0) | 2.0 (1.0, 2.0) a | 0.011 |
| Tubular atrophy and Interstitial fibrosis (%) |
15.0 (10.0, 20.0) | 20.0 (18.8, 25.0) | 20.0 (20.0, 25.0) a | 42.6 ± 12.0 a , b , c | <0.001 |
a
Focal versus mixed, crescentic, and sclerotic (p < 0.01).
b
Mixed versus crescentic and sclerotic (p < 0.01).
c
Crescentic versus sclerotic (p < 0.01).