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. 2021 Feb 4;8:622103. doi: 10.3389/fcell.2020.622103

Table 2.

Summary of organisms whose genomes were successfully edited using Cas12a and Cas12b.

Bacteria Animal Plant
Saccharomyces cerevisiae (Li Z. H. et al., 2018)
Yarrowia lipolytica (Yang et al., 2020)
Ashbya gossypii (Jiménez et al., 2020)
Aspergillus nidulans (Vanegas et al., 2019)
Clostridium beijerinckii (Zhang J. et al., 2018)
Clostridium difficile (Hong et al., 2018)
Corynebacterium glutamicum (Zhang et al., 2019)
Zymomonas mobilis (Shen et al., 2019)
Pseudomonas putida (Sun J. et al., 2018)
Streptomyces coelicolor (Li L. et al., 2018)
Mycobacterium smegmatis (Sun B. et al., 2018)
Bacillus subtilis (Wu Y. et al., 2020)
• Cyanobacterium Anabaena (Niu et al., 2019)
Chlamydomonas reinhardtii (Ferenczi et al., 2017)
• Human cell (Strecker et al., 2019a; Teng et al., 2019b)
• Zebrafish (Fernandez et al., 2018)
• Mice (Kim Y. et al., 2016; Teng et al., 2018)
• Pig (Zou et al., 2019)
Drosophila (Port and Bullock, 2016)
• Cotton (Li et al., 2019)
• Rice (Yin et al., 2019; Ming et al., 2020)
• Tobacco (Endo and Toki, 2019)
• Maize (Malzahn et al., 2019)
• Tomato (Vu et al., 2020)
• Citrus (Jia et al., 2019)
Arabidopsis thaliana (Wu F. et al., 2020)