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. 2021 Feb 2;7(2):e06113. doi: 10.1016/j.heliyon.2021.e06113

Table 1.

Optimizing the CA reaction in order to generate 9a.

Entry catalyst Solvent Yield (%) Time (h)
1 CuSO4 DMSOa 70 24
2 CuSO4 DMSO-Watera 94 15
3 CuSO4 Waterb 65 20
a

1,4-triazole as a regioselective cycloadducts.

b

a mixture of 1,5- and 1,4- triazole cycloadducts.