Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 17;11:4019. doi: 10.1038/s41598-021-83249-2

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Relationship between maternal prenatal anxiety and amygdala functional connectivity. Second trimester SCL-90-R scores were negatively correlated with functional connectivity between the left amygdala and one large cluster encompassing several brain regions shown in blue (rho = − 0.50, p = 1.2 × 10^–4). This effect was seen when controlling for child’s age at the scan, sex, birth weight, gestational age at birth, household income, and maternal prenatal depressive symptoms. The data plotted are residuals of anxiety scores and cluster-averaged left amygdala functional connectivity after accounting for covariates. Results were corrected for multiple comparisons at voxelwise and cluster p < 0.05 (cluster size: 2857 voxels; Peak: − 49, − 23, 36—left inferior parietal lobule) (N = 54).