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. 2021 Feb 17;11:4019. doi: 10.1038/s41598-021-83249-2

Table 2.

Local maxima in clusters found through Spearman correlation of anxiety scores and amygdala functional connectivity.

Area MNI coordinates at local maximum Spearman’s rho at local maximum p value
Analysis 1a
Cluster 1
 Left inferior parietal lobule − 49, − 23, 36c − 0.56 1.0 × 10–5
 Left insula − 28, − 23, 12 − 0.38  3.7 × 10–3
 Left paracentral lobule − 4, − 32, 63 − 0.40  2.9 × 10–3
 Left superior frontal gyrus − 22, − 8, 45 − 0.40  2.6 × 10–3
 Left SMA − 13, − 5, 45 − 0.35  1.0 × 10–2
 Right middle cingulate 14, − 11, 48 − 0.36  7.2 × 10–3
Analysis 2b
Cluster 1
 Left postcentral gyrus − 46, − 17, 39c − 0.59  1.0 × 10–5
 Left superior parietal lobule − 37, − 41, 54 − 0.53  6.0 × 10–5
 Left precentral gyrus − 28, − 17, 54 − 0.48  4.6 × 10–4
Cluster 2
 Right postcentral gyrus 50, − 11, 30c − 0.53  9.0 × 10–5
 Right inferior parietal lobule 50, − 32, 54 − 0.50  2.3 × 10–4
 Right superior frontal gyrus 20, − 5, 48 − 0.49  2.8 × 10–4

Cluster 1: 2857 voxels (rho = − 0.50; p = 1.2 × 10–4); Cluster 2: 2275 voxels (rho  = − 0.51; p = 1.8 × 10–4); Cluster 3: 2155 voxels (rho  = − 0.52; p = 1.1 × 10–4). These data are representative of voxel-level results.

aAnalysis 1 included age, sex, gestational age at birth, birth weight, household income and second trimester maternal depression as covariates.

bAnalysis 2 included age, sex, gestational age at birth, birth weight, household income, second trimester maternal depression as well as postnatal maternal depression and anxiety symptoms as covariates.

cCluster peak.