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. 2021 Feb 17;11:4030. doi: 10.1038/s41598-021-83612-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Ratio of IFNγ/IL10 responses across models. Graph showing the pembrolizumab-induced change in the ratio of IFNγ/IL-10 across the different in vitro models used in this study. Each point represents a donor/patient response. Mean ± SEM, n = 8 for allogeneic iDC or mDC/ T cell, n = 12 for EBV, n = 9–13 for iDC or mDC / Exhausted T cell, n = 11 for lung tumour and n = 4 for colon tumour.