Micro-CT and histological analysis. (A) Micro-CT images of premolar at 4 weeks. Scale bar = 5 mm. (B) Percent bone volume (BV/TV) of furcation defect at 4 weeks (n = 4, mean ± SD). ∗P < 0.05. (C) Histological findings of furcation defect of premolar at 4 weeks. Scale bar = 1 mm. AB, alveolar bone; F, fibrous tissue; NB, newly formed alveolar bone; R, tooth root; S-PRG, surface pre-reacted glass-ionomer.