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. 2021 Feb 4;7:610946. doi: 10.3389/fnut.2020.610946

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Copyright © 2021 Mikami, Ogita, Namai, Shigemori, Sato and Shimosato.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The effect of LTA on interleukin (IL)-17 levels in mouse splenocytes. IL-17 production in mouse splenocytes was determined in the presence and absence of IL-6/transforming growth factor (TGF)-β and various sources of LTA. Cellular supernatants were collected, and IL-17 levels were measured with ELISA. Values represent means, and error bars indicate the SD of three independent experiments. p < 0.01 by one-way analysis of variance followed by Tukey's multiple comparison test. At least three independent experiments were conducted in triplicate. HK, heat killed; SA, Staphylococcus aureus, LTA, lipoteichoic acid.