Figure 1.

Lower densities of GFAP-IR cerebral astrocytes in depressed suicides relative to controls. (A) Representative micrographs illustrating GFAP-IR astrocytes in the prefrontal cortex gray matter (PFC GM). Scale bars = 50 μm. (B–E) Depressed suicides had significantly lower densities of GFAP-IR astrocytes than controls in all regions examined except in the prefrontal cortex white matter (PFC WM), in which the difference was nearly significant. *p ≤ 0.05; n = 10; unpaired t-tests corrected for age, pH and post-mortem interval.