Figure 2.

Lower densities of VIM-IR cerebral astrocytes in depressed suicides relative to controls. (A) Representative micrographs illustrating VIM-IR astrocytes in the caudate nucleus. Scale bars = 50 μm. (B–E) Depressed suicides had significantly lower densities of GFAP-IR astrocytes than controls in the caudate nucleus, the prefrontal cortex gray matter (PFC GM) and the prefrontal cortex white matter (PFC WM). No group difference was observed in the mediodorsal thalamus, which presented exceedingly few VIM-IR astrocytes in both groups. *p ≤ 0.05; n = 10; unpaired t-tests corrected for age, pH and post-mortem interval.