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. 2021 Feb 4;12:608714. doi: 10.3389/fgene.2021.608714

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Copyright © 2021 Wang, Zhang, Liu, Zhang, Cao, Tian, Maranga, Meng, Tian, Tian, Cao, Wang, Song and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Forest plots and scatter plots of CRP-associated SNPs potential effects on intracerebral hemorrhage (ICH). Forest plot (A) shows the odds ratio (OR) with a horizontal line representing 95% CI for the CRP-associated SNP allele for ICH risk. Scatter plot (B) shows the per-allele association with ICH risk plotted against the per-allele association with 1 SD of CRP (vertical and horizontal black lines presenting the 95% CI of OR for each SNP), with the slope of each line corresponding to estimated Mendelian randomization (MR) effect per method.