Table 1.
Mendelian randomization (MR) estimates of exposure with intracerebral hemorrhage from the inverse-variance weighted (IVW) and sensitivity analysis.
| Phenotype | IVs (SNPs) | OR (95% CI) | p |
|---|---|---|---|
| CRP | |||
| IVW | 42 | 1.263 (0.935–1.704) | 0.127 |
| Weighted median | 42 | 1.458 (0.977–2.175) | 0.065 |
| Penalized weighted median | 42 | 1.466 (0.957–2.247) | 0.079 |
| MR_Egger | 42 | 1.432 (0.906–2.266) | 0.133 |
| MR-PRESSO | 42 | 1.236 (0.950–1.522) | 0.154 |
| Fibrinogen | |||
| IVW | 16 | 0.879 (0.042–18.281) | 0.933 |
| Weighted median | 16 | 0.438 (0.016–11.771) | 0.623 |
| Penalized weighted median | 16 | 0.438 (0.014–13.561) | 0.637 |
| MR_Egger | 16 | 1.663 (0.004–746.651) | 0.872 |
| MR-PRESSO | 16 | 1.221 (−1.893 to 4.335) | 0.901 |
CRP, C-reactive protein; IVW, inverse-variance weighted; MR, Mendelian randomization; WM, weighted median; PWM, penalized weighted median; OR, odds ratio; MR-PRESSO, pleiotropy residual sum and outlier; CI, confidence interval.