Fig. 5.

In-vivo assessment of XK and XKP for wound healing. (A) Process of creating an infectious rat full-thickness defect model and XKP-induced local photothermal therapy. (B) Real-time infrared thermal images and (C) photothermal heating curves of XK and XKP with 808 nm laser (1 W/cm²). (D) Shape adaptability performance test of XKP (repeated stretching–compression cycles of skin 10 times; red arrows indicate movement direction of skin). (E) Blood loss (n = 3) and (F) photographs of amputated rat tails: control, gauze, XK, and XKP. (G) Representative skin wound photographs. (H) Schematic diagram and (I) plot of wound areas (n = 3) for PBS, XK, and XKP groups on days 0, 3, 7, and 14.