Table 1.
Pathways enriched in male and female LKO livers
| ID | Term | Ca | P | Genes | Bonferroni | Benjamini | FDR |
|---|---|---|---|---|---|---|---|
| Male mice | |||||||
| Mmu 05142 | Chagas disease | 6 | 5.23E-03 | ADCY1, CCL3, CCL2, GNAI1, SERPINE1, PIK3R5 | 6.27E-01 | 6.27E-01 | 6.29E+00 |
| Mmu 04914 | Progesterone-mediated oocyte maturation | 5 | 1.48E-02 | ADCY1, PLK1, GNAI1, PKMYT1, PIK3R5 | 9.40E-01 | 7.55E-01 | 1.69E+01 |
| Mmu 04015 | Rap1 signaling pathway | 7 | 2.91E-02 | PRKD1, ADCY1, GNAI1, FPR1, PIK3R5, ANGPT2, ITGAM | 9.96E-01 | 8.43E-01 | 3.07E+01 |
| Mmu 05146 | Amoebiasis | 5 | 3.87E-02 | LAMA4, ADCY1, PIK3R5, COL5A2, ITGAM | 9.99E-01 | 8.44E-01 | 3.87E+01 |
| Mmu 04670 | Leukocyte transendothelial migration | 5 | 3.98E-02 | VCAM1, GNAI1, CLDN6, PIK3R5, ITGAM | 1.00E+00 | 7.83E-01 | 3.96E+01 |
| Female mice | |||||||
| Mmu 05204 | Chemical carcinogenesis | 5 | 2.31E-06 | GSTA1, UGT2B38, GSTA2, CYP2C55, SULT2A1 | 7.16E-05 | 7.16E-05 | 1.98E-03 |
| Mmu 00980 | Metabolism of xenobiotics by cytochrome P450 | 4 | 4.46E-05 | GSTA1, UGT2B38, GSTA2, SULT2A1 | 1.38E-03 | 6.90E-04 | 3.83E-02 |
| Mmu 00982 | Drug metabolism cytochrome P450 | 3 | 2.51E-03 | GSTA1, UGT2B38, GSTA2 | 7.50E-02 | 2.57E-02 | 2.14E+00 |
| Mmu 00140 | Steroid hormone biosynthesis | 3 | 4.32E-03 | UGT2B38, CYP2C55, HSD3B5 | 1.26E-01 | 3.30E-02 | 3.66E+00 |
| Mmu 00040 | Pentose and glucuronate interconversions | 2 | 3.80E-02 | UGT2B38, AKR1B7 | 6.99E-01 | 2.13E-01 | 2.83E+01 |
a
Refers to count.