Table 4.
Significant predictors, all χ2(df = 2–4, N = 48) > 16, all ps < .05, FDR-corrected for multiple comparisons, for each of the Western Aphasia Battery–Revised standard scores included PWA characteristics including lesion volume, apraxia of speech (AOS) severity, and age, as well as functional connectivity among regions of interest in the frontal, temporal, and parietal lobes and involving unilateral (right [R], left [L]) and bilateral (B) connections.
| Predictor | Aphasia Quotient | Spontaneous Speech | Content | Fluency | Auditory Comprehension | Repetition | Naming and Word Finding | ||
|---|---|---|---|---|---|---|---|---|---|
| Lesion volume | Larger lesion = lower score | Larger lesion = lower score | Larger lesion = lower score | Larger lesion = lower score | Larger lesion = lower score | ||||
| AOS severity | More severe AOS = lower score | More severe AOS = lower score | More severe AOS = lower score | More severe AOS = lower score | |||||
| Age | Older = better score | ||||||||
| Connection location | |||||||||
| Frontal | L | lIFG-lMFG | Weaker FC = lower score | ||||||
| Frontotemporal | R | rpMTG-rIFG | Weaker FC = lower score | Weaker FC = lower score | |||||
| Temporal | B | lFusi-riITG | Stronger FC = higher score | ||||||
| Temporoparietal | L | lAG-lsITG | Stronger FC = higher score | ||||||
| Parietal | B | lAG-rAG | Stronger FC = higher score | ||||||
Note. FC = functional connectivity; l = left; r = right; IFG = inferior frontal gyrus; MFG = middle frontal gyrus; pMTG = posterior middle temporal gyrus; iITG = inferior inferior temporal gyrus; Fusi = fusiform gyrus; AG = angular gyrus; sITG = superior inferior temporal gyrus.
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