Table 1.
Demographic, clinical, and immunological data for septic shock patients.
| Parameters | Septic shock Patients (n=12) |
|---|---|
| Age at admission (years) | 69 [63–73] |
| Gender - Male, n (%) | 7 (58) |
| Main admission category | |
| Medical, n (%) | 4 (33) |
| Surgical, n (%) | 8 (67) |
| SAPS II score | 53 [50–62] |
| SOFA score | 9 [8-10] |
| McCabe score | |
| 0, n (%) | 6 (50) |
| 1, n (%) | 6 (50) |
| Infection diagnosis, n* (%) | |
| Microbiology | 10 (91) |
| Surgery | 1 (9) |
| Microbiologicaly documented, n(%) | |
| Bacilli gram - | 6 (40) |
| Cocci gram + | 9 (60) |
| Other | 0 (0) |
| Site of infection, n* (%) | |
| Pulmonary | 1 (9) |
| Abdominal | 3 (27) |
| 28-day non survivors, n (%) | 2 (17) |
| Secondary nosocomial infections, n (%) | 3 (25) |
| Immunological parameters | |
| mHLA-DR (AB/C) | 4044 [3,246–6,210] |
| Absolute CD4+ T cell count | 317 [248–463] |
Continuous data and biological parameters are presented as medians and interquartile ranges [Q1–Q3]. For clinical parameters, categorical data are presented as numbers of cases and percentages among the total population in brackets. SAPS II (Simplified Acute Physiology Score II) and McCabe scores were calculated after admission. SOFA (Sequential Organ Failure Assessment) score was measured after 24h of ICU stay. mHLA-DR was expressed as numbers of anti-HLA-DR antibodies bound per monocyte (AB/C). Reference values for healthy volunteers: mHLA-DR: > 15,000 AB/C, CD4+: 336-1126 cells/µl.