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. 2021 Feb 4;11:570170. doi: 10.3389/fphys.2020.570170

TABLE 2.

Studies published in the last 10 years with cancer patients.

Author Subjects Cachexia markers Exercise training protocol
Main results
Type Protocol Volume/intensity
Grote et al. (2018) Oncologic patients with diagnosed cachexia ↓Body weight ↓Functional capacity Progressive resistance training 13 training sessions, 3 times weekly for 30 min 3 exercises for major muscle groups with 8–12 repetition maximum • Improvement of weight loading
• Improvement in general fatigue and quality of life in the intervention group
Solheim et al. (2017) Oncologic patients with diagnosed cachexia Body mass index < 30 kg/m2; and < 20% weight loss in the previous 6 months Multimodal treatment: anti-inflammatory drug; Eicosapentaenoic Acid (EPA); Nutritional counseling; and Exercise program including home-based aerobic and resistance training Aerobic exercise as patients’ choice and resistance training AT for 30 min a Day, 2 times a week; RT consisted in six individualized exercises, three times weekly for about 20 min • No statistically significant effect on physical activity or muscle mass
• Survival was similar between the groups
Rogers et al. (2011) Oncologic patients with diagnosed cachexia ↓Body weight ↓Functional capacity Resistance Training + EPA or Cox-2 Inhibitor 20 weeks of RT. 5-10 min warm up, followed by the exercise prescription, and a 5 min cool-down Not mentioned • Increase in grip strength
• Increase in body weight
• Improved levels of fatigue
• Decreasing CRP and interleukin-6

EPA, eicosapentaenoic acid; COX-2, cardiomyocyte cyclooxygenase-2; CRP, C-reactive protein.