TABLE 2.
Author | Subjects | Cachexia markers |
Exercise training protocol |
Main results | ||
Type | Protocol | Volume/intensity | ||||
Grote et al. (2018) | Oncologic patients with diagnosed cachexia | ↓Body weight ↓Functional capacity | Progressive resistance training | 13 training sessions, 3 times weekly for 30 min | 3 exercises for major muscle groups with 8–12 repetition maximum | • Improvement of weight loading • Improvement in general fatigue and quality of life in the intervention group |
Solheim et al. (2017) | Oncologic patients with diagnosed cachexia | Body mass index < 30 kg/m2; and < 20% weight loss in the previous 6 months | Multimodal treatment: anti-inflammatory drug; Eicosapentaenoic Acid (EPA); Nutritional counseling; and Exercise program including home-based aerobic and resistance training | Aerobic exercise as patients’ choice and resistance training | AT for 30 min a Day, 2 times a week; RT consisted in six individualized exercises, three times weekly for about 20 min | • No statistically significant effect on physical activity or muscle mass • Survival was similar between the groups |
Rogers et al. (2011) | Oncologic patients with diagnosed cachexia | ↓Body weight ↓Functional capacity | Resistance Training + EPA or Cox-2 Inhibitor | 20 weeks of RT. 5-10 min warm up, followed by the exercise prescription, and a 5 min cool-down | Not mentioned | • Increase in grip strength • Increase in body weight • Improved levels of fatigue • Decreasing CRP and interleukin-6 |
EPA, eicosapentaenoic acid; COX-2, cardiomyocyte cyclooxygenase-2; CRP, C-reactive protein.