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. 2021 Feb 4;9:624082. doi: 10.3389/fcell.2021.624082

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Copyright © 2021 Krautter and Iqbal.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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N- and O-glycan differ in their core structure. (A) Various carbohydrates are making up mammalian glycans. (B) N-glycans share a common core structure. The carbohydrates added to the core structure define the three subtypes of N-glycans: high-mannose, hybrid and complex. (C) O-glycans discussed in this review are based on core 1 or core 2 O-glycans.