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Representative immunohistochemical images of MSI/MSS GC (×200). MLH1, PMS2, MSH2 and MSH6 were all localized in GC cell nucleus. The brown yellow was considered positive, while the absence of staining was considered negative. MSI GC: MLH1 and PMS2 were negative(A,B), MSH2 and MSH6 were positive(C,D); MSS GC: MLH1, PMS2, MSH2 and MSH6 were all positive(E-H).
