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. 2021 Jan 18;12(6):1698–1707. doi: 10.7150/jca.40500

Figure 2.

Figure 2

Representative immunohistochemical images of PD1, PDL1[T], PDL1, CD8 and CD68 in MSI and MSS GC (×200). PD1, PDL1[T], PDL1, CD8 and CD68 were all localized in the membrane and/or cytoplasm. PD1, CD8 and CD68 was all stained in tumor infiltrating immune cells, while PDL1 was stained in tumor cells (labeled as PDL1[T]) and tumor infiltrating immune cells (labeled as PDL1). PD1, PDL1[T] and PDL1 expression in MSI GC was greater than those in MSS GC (P=0.109,0.090 and 0.044, respectively). CD8+T cells/CD68+M density in MSI GC was higher than those in MSS GC (P=0.537 and <0.001, respectively).