Table 4.
Sensitivity analysis of studies evaluated F.nuleatum on clinicopathological characteristics of CRC
| Factors | No. of studies | No. of patients | Pooled OR (95%CI) | P-value | Heterogenelty | Statistical method | |
|---|---|---|---|---|---|---|---|
| I2 (%) | P-value | ||||||
| Tumor side | 8 | 3035 | 1.17 (0.77, 1.77) | 0.47 | 67% | 0.003 | Random |
| TNM Stage | 7 | 2662 | 1.05 (0.80~1.36) | 0.74 | 2% | 0.41 | Fixed |
| T stage | 6 | 2249 | 2.14 (1.56, 2.93) | <0.00001 | 0% | 0.46 | Fixed |
| N stage | 5 | 2067 | 1.01 (0.74, 1.38) | 0.94 | 0% | 0.43 | Fixed |
| OS | 5 | 1789 | 1.36 (1.16, 1.61) | 0.0002 | 0% | 0.63 | Fixed |
| DFS | 3 | 1119 | 1.68 (1.22, 2.32) | 0.002 | 0% | 0.74 | Fixed |
OS overall survival, DFS disease-free survival.