Table 2.
VWF cleavage in plasma samples from 10 COVID-19 patients following ex vivo incubation 1 IU/mL rADAMTS13.
| Sample number | VWF:CB (IU/mL) |
Percentage decrease in VWF:CB (0 vs. 5 h) |
VWF dimer relative to total VWF multimers (AUC %) |
Percentage increase in VWF dimer (0 vs. 5 h) |
||
|---|---|---|---|---|---|---|
| 0 h | 5 h | 0 h | 5 h | |||
| S21 | 3.70 | 1.63 | 44 | 4.9 | 8.5 | 173 |
| S6 | 2.19 | 0.73 | 33 | 5.4 | 7.0 | 130 |
| S10 | 6.48 | 3.91 | 60 | n.d. | n.d. | – |
| S12 | 3.01 | 1.60 | 53 | n.d. | n.d. | – |
| B1 | 3.09 | 2.02 | 65 | 3.6 | 9.1 | 253 |
| B2 | 1.39 | 0.84 | 60 | 5.4 | 11.3 | 209 |
| B5 | 2.46 | 1.61 | 65 | 3.7 | 11.0 | 297 |
| B7 | 3.03 | 1.58 | 52 | 5.3 | 10.1 | 191 |
| B15 | 2.44 | 1.08 | 44 | 5.1 | 12.3 | 241 |
| B18 | 2.25 | 1.42 | 63 | 3.6 | 7.0 | 194 |
n.d. not done;