Table 3.

Univariate and multivariate analysis for OS in patients with ICC.

Gene symbol	Univariate COX regression		Multivariate COX regression
	HR (95% CI)	P	HR (95% CI)	P	Coefficient
ANXA1	1.019 (1.003, 1.034)	0.019
GLIPR1	1.076 (1.010, 1.146)	0.023
TMEM107	1.295 (1.017, 1.648)	0.036
MT2A	1.004 (1.001, 1.007)	0.009
PMEPA1	1.009 (1.001, 1.018)	0.038
VIM	1.002 (1.000, 1.003)	0.043
SLC16A3	1.070 (1.016, 1.127)	0.010	0.686 (0.538, 0.875)	0.002	−0.377
BNIP3L	1.095 (1.004, 1.194)	0.041	1.239 (1.013, 1.516)	0.037	0.214
TPM2	1.014 (1.003, 1.024)	0.008	1.265 (1.109, 1.442)	0.000	0.235
CLEC11A	1.075 (1.001, 1.155)	0.046	0.767 (0.648, 0.909)	0.002	−0.265
EREG	1.135 (1.018, 1.266)	0.023	1.349 (0.956, 1.904)	0.088	0.300
PMAIP1	1.053 (1.004, 1.103)	0.033	0.397 (0.237, 0.665)	0.000	−0.925
CEBPB	1.020 (1.004, 1.036)	0.016	1.074 (1.032, 1.118)	0.000	0.072
A2M	1.008 (1.001, 1.015)	0.016	1.031 (1.015, 1.047)	0.000	0.030
TUBA1B	1.034 (1.007, 1.063)	0.014	1.129 (1.053, 1.211)	0.001	0.121