Table 6. Stratified analyses between miR-499a rs3746444 A>G polymorphism and NSCLC risk by age, sex, smoking, drinking and BMI.

Variable	miRNA-499a rs3746444 A>G (case/control)1			Adjusted OR2 (95% CI); P
	AA	AG	GG	AG vs. AA	GG vs. AA	GG/AG vs. AA	GG vs. AA/AG
Sex
Male	444/415	172/152	20/17	1.05 (0.79–1.38); P: 0.744	1.59 (0.79–3.21); P: 0.199	1.09 (0.84–1.43); P: 0.509	1.57 (0.78–3.16); P: 0.209
Female	370/342	158/119	16/8	1.21 (0.91–1.61); P: 0.194	1.84 (0.77–4.41); P: 0.172	1.25 (0.95–1.65); P: 0.118	1.74 (0.73–4.17); P: 0.211
Age
<59	367/338	144/101	15/11	1.30 (0.95–1.78); P: 0.096	1.68 (0.72–3.92); P: 0.233	1.33 (0.99–1.80); P: 0.060	1.57 (0.67–3.65); P: 0.297
≥59	447/419	186/170	21/14	1.03 (0.79-1.33); P: 0.854	1.71 (0.84-3.51); P: 0.141	1.07 (0.84–1.38); P: 0.583	1.70 (0.83–3.47); P: 0.144
Smoking status
Never	511/618	209/215	28/21	1.17 (0.93–1.48); P: 0.176	1.91 (1.08–3.48); P: 0.035	1.23 (0.99–1.54); P: 0.066	1.82 (1.00–3.32); P: 0.049
Ever	303/139	121/56	8/4	1.04 (0.71–1.52); P: 0.856	0.90 (0.26–3.13); P: 0.873	1.03 (0.71–1.49); P: 0.889	0.90 (0.26–3.09); P: 0.861
Alcohol consumption
Never	629/695	274/247	33/23	1.19 (0.97–1.47); P: 0.101	1.86 (1.06–3.29); P: 0.032	1.25 (1.02–1.53); P: 0.035	1.77 (1.01–3.12); P: 0.047
Ever	185/62	56/24	3/2	0.75 (0.42–1.32); P: 0.314	0.43 (0.07–2.65); P: 0.360	0.72 (0.41–1.25); P: 0.245	0.46 (0.07–2.82); P: 0.398
BMI (kg/m2)
<24	535/413	230/139	25/17	1.30 (1.01–1.68); P: 0.042	1.31 (0.68–2.52); P: 0.419	1.30 (1.02–1.67); P: 0.034	1.22 (0.64–2.33); P: 0.555
≥24	279/344	100/132	11/8	0.90 (0.65–1.23); P: 0.495	2.54 (0.98–6.55); P: 0.054	0.97 (0.71–1.32); P: 0.854	2.61 (1.02–6.73); P: 0.046

¹For miR-499a rs3746444 A>G, the genotyping was successful in 1180 (98.91%) NSCLC cases and 1053 (99.72%) controls.

²Adjusted for age, sex, smoking, drinking and BMI (besides stratified factors accordingly) in a multiple logistic regression model.