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. 2021 Feb 3;11:573156. doi: 10.3389/fimmu.2020.573156

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Copyright © 2021 Fazzi, Petrini, Giuliani, Morganti, Carulli, Dalla Palma, Notarfranchi, Galimberti and Buda

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Average with standard deviation of the number of γδ lymphocytes before the beginning and after 8 days of treatment at cycles: 1, 2, 3, 6, 9, and 12. (B) Ratio between the number of γδ lymphocytes at day 8 and day 1 of cycle 1 for each patient. (C) Time to progression of patients with a high and low (dotted line) percentage of γδ lymphocytes (according to the median value) in bone marrow before the beginning of the maintenance treatment. (D) Average with standard deviation of the number of CD3+ Treg lymphocytes before the beginning and after 8 days of treatment at cycles: 1, 3, and 6. Stars indicate statistically significant differences.