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. Author manuscript; available in PMC: 2021 Jun 1.
Published in final edited form as: Cancer Metastasis Rev. 2020 Jun;39(2):397–414. doi: 10.1007/s10555-020-09875-w

Table 1.

Different forms of cellular senescence

RS Replicative senescence Senescence induced by telomere shortening
SIPS Stress-induced premature senescence Senescence induced by cellular stress
OIS Oncogene-induced senescence Senescence induced by oncogene expression
LTSIS Loss of tumor suppressor gene-induced senescence Senescence induced by loss of tumor suppressor gene expression
SASP Senescent-associated secretory phenotype Cytokines, chemokines, growth factors, and metalloproteinases secreted by senescent cells