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. 2021 Feb 17;78(5):1–8. doi: 10.1001/jamapsychiatry.2020.4564

Table. Results of Secondary Analyses Examining Baseline Depression Severity, and Randomized Clinical Trial Publication Year.

Factor bln σ̂ (95% CI)a P value
Baseline depression
Baseline depression × AD 0.99 (0.96-1.02) .58
Baseline depression mean 1.08 (1.04-1.12) <.001
AD (compared with placebo) 1.00 (0.97-1.03) .83
End point mean 1.04 (1.00-1.07) .03
Publication year
Publication year × AD 0.999 (0.996-1.002) .42
Publication year 0.998 (0.994-1.002) .36
AD (compared with placebo) 1.040 (1.000-1.079) .048
End point mean 1.081 (1.040-1.116) <.001

Abbreviation: AD, antidepressant.

a

bln σ̂ reflects the association of each predictor with ln σ̂.