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. 2021 Feb 18;17(2):e9840. doi: 10.15252/msb.20209840

Figure 2. Challenges with residue‐level mapping and UniProtKB canonical protein sequences.

Figure 2

  1. Schematic depiction of mapping scenarios from updating chemoproteomic‐detected protein sequences using stable or versioned identifiers.
  2. Distribution of number of isoforms per stable UniprotKB ID for 3,953 detected proteins.
  3. Frequency of specific isoform name for 2,487 multi‐isoform UniProtKB canonical proteins.
  4. Schematic depiction of glucose‐6‐phosphate dehydrogenase (G6PD, UniProtKB ID P11413) cross‐referencing both identical and non‐identical sequences of Ensembl stable IDs from five releases.
  5. Heatmap of protein sequence distance scores for detected UniProtKB and cross‐referenced Ensembl proteins from five releases. Each gene name corresponds to one unique stable Ensembl protein ID.