Table. Clinical Characteristics of 675 Study Patients.
| Characteristics | No. (%)a |
|---|---|
| Age, median (IQR), y | 63 (53-72) |
| Age group, y | |
| 18-44 | 92 (14) |
| 45-64 | 267 (40) |
| 65-74 | 199 (29) |
| 75-84 | 102 (15) |
| ≥85 | 15 (2) |
| Sex | |
| Female | 270 (40) |
| Male | 405 (60) |
| Race/ethnicityb | |
| Non-Hispanic White | 259 (38) |
| Hispanic | 286 (42) |
| Native American | 68 (10) |
| Black | 28 (4) |
| Body mass index, median (IQR)c | 33 (29-39) |
| Medications | |
| Dexamethasone | 255 (36) |
| Remdesivir | 326 (48) |
| Anticoagulants | 607 (90) |
| Norepinephrine | 33 (5) |
| Comorbidities | |
| Diabetes | 413 (61) |
| Hypertension | 500 (74) |
| Coronary artery disease | 134 (20) |
| Chronic obstructive lung disease | 112 (17) |
| Cancer | 67 (10) |
| Laboratory values, median (IQR) | |
| C-reactive protein, mg/L | 168 (96-260) |
| D-dimer, μg/mL | 1.76 (0.93-4.66) |
| Brain-type natriuretic peptide, pg/mL | 461 (180-1328) |
| Creatinine, mg/dLd | 0.9 (0.65-1.30) |
| Bilirubin, mg/dLd | 0.6 (0.4-0.9) |
| Ratio of Pao2 to Fio2d | 56 (50-68) |
| Platelets, ×103/μLd | 225 (164-299) |
| Arterial pressure, mean (IQR), mm Hgd | 74 (64-84) |
| Glasgow Coma Scale score, median (IQR)d | 15 (13-15) |
Abbreviations: IQR, interquartile range; Fio2, fraction of inspired oxygen.
SI conversion factors: To convert bilirubin to μmol/L, multiply by 17.104; creatinine to μmol/L, multiply by 88.4; D-dimer to nmol/L, multiply by 5.476.
a
Unless otherwise indicated.
b
Self-reported at hospital admission and was assessed to aid consideration of the generalizability of the study findings.
c
Calculated as weight in kilograms divided by height in meters squared.
d
Indicates the variables that were incorporated into the Sequential Organ Failure Assessment score.