Table 4.

Summary of findings for studies of acceptable quality

Author, Year	Origin of study sample	Study population	Interventions	Time of follow-up	Outcome variables	SMT superior to control
Asthma
Balon, 1998 [84]	Chiropractic patients	Children (7–16 years) with mild or moderate asthma	SMT vs. Sham	2 and 4 months	FEV1 PEF Quality of life	No
Infantile Colic
Olafsdottir, 2001 [87]	Public health care clinics, pediatric outpatient clinic at University hospital, general practitioners, chiropractors and direct referrals	Infants with colic	SMT vs. Sham	8–14 days after intervention	Parent’s global perceived improvement or crying time	No
Hypertension
Goertz, 2016 [81]	Community in Iowa, USA	Adults with pre-hypertension or hypertension	SMT vs. Sham	Immediately and 6 weeks	Blood pressure	No
Ward, 2015 [80]	Community in Texas, USA	Adults with hypertension	SMT vs. Sham	Immediately and 10 min	Blood pressure, pulse pressure, mean arterial pressure and heart rate	No
Dysmenorrhea
Hondras, 1999 [37]	Chiropractic patients	Women with primary dysmenorrhea	SMT vs. Sham	1 h	VAS or MMDQ	No
Migraine
Chaibi, 2017 [82]	University hospital, general practitioners and community in Oslo Counties, Norway	Adults with migraine	SMT vs. Sham	Immediately, 3 months	Migraine days	No (Sham significantly superior to SMT)
				6 and 12 months	Migraine duration, intensity or headache index	No

Legend: FEV1 forced expiratory volume in 1 s, PEF peak expiratory flow, SMT spinal manipulative therapy, MDQ Moos’ menstrual distress questionnaire, mths months, NS non-significant, VAS visual analog scale