Figure 2.

Temporal profile of the viral load in patient 1 with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) reinfection. WGS of SARS-CoV-2 from respiratory specimens was performed at 4 time points (at first admission with initial diagnosis, during follow-up, at second admission with reinfection, at third admission with retest positive again). A lower Ct value corresponds to a higher viral load. The values under the dashed line were interpreted as negative for SARS-CoV-2. Viral culture was conducted by inoculating upper (triangle) or lower (star) respiratory tract specimens onto Vero cells. Blue indicates that SARS-CoV-2 was culturable and gray indicates that SARS-CoV-2 was not culturable. *No intact viral genome was observed at third admission. Abbreviations: Ct, cycle threshold; rRT-PCR, real-time reverse-transcription polymerase chain reaction; WGS, whole-genome sequencing.