Table 4.
Medication | POR prevention | Treatment of POR |
---|---|---|
Curcumin | –53 | ? |
Enteral nutrition | +70–72 | ? |
Nitroimidazole/antibiotics | +38,39 | – |
Mesalamine | –31,63 | –34 |
Budesonide | –48,49 | ?a |
Thiopurines | +31,41,42 | +34 |
Anti-TNF | +++55–59,62–64 | +++60 |
Vedolizumab | ++?68 | ? |
Ustekinumab | ++?69 | ? |
Authors opinion. Budesonide may be used for short term induction therapy, but similar to luminal ileal CD, is not likely effective for long-term therapy.
CD, Crohn’s disease; POR, postoperative recurrence; TNF, tumor necrosis factor.