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. 2021 Feb 15;14:1756284821993581. doi: 10.1177/1756284821993581

Table 4.

Efficacy of various therapies and knowledge gaps for the prevention and treatment of POR.

Medication POR prevention Treatment of POR
Curcumin 53 ?
Enteral nutrition +7072 ?
Nitroimidazole/antibiotics +38,39
Mesalamine 31,63 34
Budesonide 48,49 ?a
Thiopurines +31,41,42 +34
Anti-TNF +++5559,6264 +++60
Vedolizumab ++?68 ?
Ustekinumab ++?69 ?
a

Authors opinion. Budesonide may be used for short term induction therapy, but similar to luminal ileal CD, is not likely effective for long-term therapy.

CD, Crohn’s disease; POR, postoperative recurrence; TNF, tumor necrosis factor.