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. 2021 Feb 14;14:2516865720986231. doi: 10.1177/2516865720986231

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© The Author(s) 2021

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 6. — Kaplan-Meier EFS curves for molecular subgroups of CRC patients. TS ⩽ 2.98 and TS > 2.98 (a), TP ⩽ 6.92 and TP > 6.92 (b), DPD ⩽ 4.26 and DPD > 4.26 (c) and COX2 ⩽ 3.95 and COX2 > 3.95 (d).

The baseline median relative expression of TS, TP, DPD and COX2 genes normalised to β-actin for 43 CRC patients were 2.98, 6.92, 4.26 and 3.95, respectively. Patients were stratified around the medians calculated for the 4 genes’ baseline expression levels, and then the time to recurrence or progression was calculated with Kaplan-Meier test of survival.