Table 2.
Binary logistic regression for the risk for functional disability (defined as HAQ-DI >1).
| Variables | Odds ratio | 95% CI | p value |
|---|---|---|---|
| Overall sample – Model 1 | |||
| CSI score | 1.079 | 1.039–0.119 | <0.01 |
| Disease duration | 1.020 | 0.956–1.088 | NS |
| Age | 1.060 | 1.012–1.111 | 0.01 |
| BMI | 1.006 | 0.896–1.129 | NS |
| Remission* | Ref. | ||
| Low disease activity | 2.950 | 0.437–19.936 | NS |
| Moderate disease activity | 10.879 | 1.796–65.905 | <0.01 |
| High disease activity | 37.039 | 4.876–281.370 | <0.01 |
| Overall sample – Model 2 | |||
| CSI score ⩽29 | Ref. | ||
| CSI score 30–39 | 1.370 | 0.213–8.822 | NS |
| CSI score 40–49 | 7.241 | 1.538–34.081 | 0.01 |
| CSI score ⩾50 | 17.108 | 3.711–78.876 | <0.01 |
| Disease duration | 1.018 | 0.954–1.086 | NS |
| Age | 1.055 | 1.006–1.108 | 0.02 |
| BMI | 1.001 | 0.887–1.128 | NS |
| Remission* | Ref. | ||
| Low disease activity | 2.673 | 0.384–18.602 | NS |
| Moderate disease activity | 10.796 | 1.784–66.664 | 0.01 |
| High disease activity | 40.965 | 5.135–326.783 | <0.01 |
| RA – Model 1 | |||
| CSI score | 1.049 | 0.989–1.114 | NS |
| Disease duration | 1.050 | 0.952–1.159 | NS |
| Age | 1.101 | 1.015–1.194 | 0.02 |
| BMI | 1.055 | 0.901–1.235 | NS |
| SDAI | 1.124 | 1.035–1.221 | <0.01 |
| RA – Model 2 | |||
| CSI score ⩽29 | Ref. | ||
| CSI score 30–39 | 2.554 | 0.181–36.002 | NS |
| CSI score 40–49 | 37.264 | 2.663–521.389 | <0.01 |
| CSI score ⩾50 | 5.272 | 0.344–80.827 | NS |
| Disease duration | 1.078 | 0.962–1.209 | NS |
| Age | 1.127 | 1.018–1.247 | 0.02 |
| BMI | 1.092 | 0.917–1.301 | NS |
| SDAI | 1.150 | 1.039–1.273 | <0.01 |
| PsA – Model 1 | |||
| CSI score | 1.102 | 1.037–1.171 | <0.01 |
| Disease duration | 1.010 | 0.867–1.176 | NS |
| Age | 1.020 | 0.958–1.085 | NS |
| BMI | 0.977 | 0.810–1.177 | NS |
| DAPSA | 1.058 | 0.982–1.141 | NS |
| PsA – Model 2 | |||
| CSI score ⩽29 | Ref. | ||
| CSI score 30–39 | 1.674 | 0.072–38.790 | NS |
| CSI score 40–49 | 4.078 | 0.326–51.071 | NS |
| CSI score ⩾50 | 31.173 | 2.352–413.133 | <0.01 |
| Disease duration | 0.998 | 0.857–1.164 | NS |
| Age | 1.023 | 0.962–1.089 | NS |
| BMI | 0.963 | 0.791–1.173 | NS |
| DAPSA | 1.067 | 0.977–1.165 | NS |
*
SDAI and DAPSA were pooled together according to the respective cut-offs.
BMI, body mass index; CI, confidence interval; CSI, central sensitization index; DAPSA, Disease Activity in Psoriatic Arthritis; HAQ-DI, Health Assessment Questionnaire Disability Index; NS, not significant; PsA, psoriatic arthritis; RA, rheumatoid arthritis; Ref., reference; SDAI, Simple Disease Activity Index.