Table 1.
Characteristics of patients.
|
DEFERRED RRT
|
EARLY RRT | |||||||
|
Factor
|
N
|
%
|
|
N
|
%
|
p
|
stan diff
|
|
| Diuretic prior daya | 35 | 21 | 36 | 21 | 0.999 | 1.5 | ||
| Diuretic todaya | 20 | 12 | 19 | 11 | 0.999 | 1.9 | ||
| Vasopressor prior daya | 47 | 28 | 50 | 30 | 0.810 | 3.9 | ||
| Vasopressor todaya | 111 | 66 | 118 | 70 | 0.485 | 8.9 | ||
| Female | 55 | 33 | 73 | 43 | 0.057 | 22.1 | ||
| Diagnosis | <0.001 | |||||||
| ARDS | 11 | 7 | 29 | 17 | ||||
| Transplants | 15 | 9 | 18 | 11 | ||||
| Sepsis | 38 | 22 | 31 | 18 | ||||
| Other | 105 | 62 | 91 | 54 | ||||
|
Factor
|
N
|
median
|
IQ
|
N
|
median
|
IQ
|
p
|
stan diff
|
| Age (y) | 153 | 61 | 52, 70 | 153 | 57 | 46, 64 | 0.004 | 29.6 |
| Prior day’s values | ||||||||
| Urine (mL)a | 141 | 775 | 290, 1801 | 141 | 560 | 215, 1865 | 0.551 | 9.0 |
| Fluid balance (mL) | 136 | 287 | −941, 2188 | 139 | 969 | −308, 2993 | 0.085 | 17.8 |
| Creatinine (µmol/L)a,b | 169 | 221 | 110, 327 | 169 | 274 | 164, 385 | 0.005 | 9.3 |
| BUN (mmol/L)a,b | 169 | 18 | 12, 24 | 169 | 18 | 12, 25 | 0.599 | 9.0 |
| Potassium (mmol/L)a | 169 | 4.3 | 4.0, 4.9 | 169 | 4.4 | 4.0, 5.0 | 0.390 | 3.1 |
| Bicarbonate (mmol/L)a | 169 | 22 | 19, 25 | 169 | 22 | 19, 25 | 0.875 | 0.8 |
| Current day’s values | ||||||||
| Creatinine (µmol/L)a,b | 169 | 230 | 124, 352 | 169 | 256 | 175, 354 | 0.066 | 3.2 |
| BUN (mmol/L) a,b | 169 | 18 | 13, 28 | 169 | 16 | 11, 24 | 0.351 | 6.0 |
| Potassium (mmol/L)a | 169 | 4.4 | 4.0, 4.9 | 169 | 4.5 | 4.0, 5.0 | 0.717 | 0.5 |
| Bicarbonate (mmol/L)a | 169 | 22 | 18, 25 | 169 | 22 | 19, 25 | 0.407 | 5.1 |
| Fluid input (mL) | 169 | 1912 | 1260, 3509 | 169 | 2656 | 1747, 4457 | <0.001 | 18.4 |
| Fluid output (mL) | 169 | 1135 | 550, 2248 | 169 | 1814 | 710, 3162 | 0.004 | 23.7 |
| Fluid balance (mL) | 169 | −48 | −1940, 1325 | 169 | −378 | −2143, 1165 | 0.385 | 1.1 |
| Urine today (mL)a | 169 | 950 | 352, 1951 | 169 | 1208 | 250, 2319 | 0.159 | 9.3 |
| APACHE III Score | 169 | 75 | 61, 88 | 169 | 90 | 75, 110 | <0.001 | 68.0 |
| Heart rate (/min) | 169 | 91 | 79, 103 | 169 | 94 | 78, 107 | 0.378 | 11.6 |
| Respirations (/min) | 166 | 20 | 16, 24 | 161 | 22 | 16, 26 | 0.081 | 13.3 |
| Temperature (℃) | 166 | 36.9 | 36.6, 37.4 | 163 | 36.8 | 36.5, 37.2 | 0.006 | 30.2 |
|
Factor
|
N
|
median
|
IQ
|
N
|
median
|
IQ
|
p
|
stan diff
|
| Systolic blood pressure (kPa) | 169 | 15.2 | 13.3, 16.9 | 169 | 14.8 | 13.3, 16.9 | 0.628 | 1.1 |
| Diastolic blood pressure (kPa) | 169 | 7.2 | 6.5, 8.4 | 168 | 7.3 | 6.4, 8.9 | 0.855 | 2.2 |
| Sodium (mmol/L) | 169 | 139 | 136, 142 | 169 | 140 | 137, 144 | 0.086 | 9.0 |
| Phosphorous (mmol/L) | 163 | 1.61 | 1.16, 2.36 | 164 | 1.78 | 1.49, 2.39 | 0.029 | 13.5 |
| Magnesium (mmol/L) | 164 | 0.95 | 0.86, 1.07 | 164 | 0.99 | 0.91, 1.11 | 0.003 | 25.7 |
| Glucose high (mmol/L) | 166 | 7.71 | 6.55, 9.38 | 165 | 8.71 | 7.38, 10.6 | <0.001 | 41.5 |
| Glucose low (mmol/L) | 166 | 5.94 | 5.16, 6.83 | 165 | 5.94 | 5.11, 6.94 | 0.914 | 1.9 |
| Albumin (g/L) | 95 | 27 | 24, 31 | 125 | 28 | 24, 32 | 0.782 | 3.0 |
| Hemoglobin (g/L) | 164 | 81 | 74, 93 | 163 | 78 | 70, 86 | 0.011 | 25.2 |
| Platelets (109/L) | 164 | 141 | 85, 211 | 163 | 97 | 48, 177 | 0.001 | 19.6 |
| Bilirubin (µmol/L) | 94 | 23.9 | 10.3, 78.8 | 125 | 35.9 | 15.4, 101 | 0.049 | 26.4 |
Note: All current day values are based on values up to 12 noon of that day. If more than one lab value was determined, the highest creatinine, BUN, potassium, phosphorous, magnesium, bilirubin values are displayed; while the lowest bicarbonate, sodium, hemoglobin, and platelets values are displayed. aVariables in the propensity match.
To facilitate comparisons with other studies that used mean and standard deviation to describe creatinine and BUN, our mean and standard deviation for creatinine for the prior day were 277 ± 272 µmol/L in the DEFERRED group vs. 298 ± 182 in the EARLY group, p = 0.393; for BUN for the prior day, it was 19 ± 10 mmol/L vs. 20 ± 11, p = 0.411; for current day’s creatinine, it was 283 ± 236 vs. 290 ± 176, p = 0.765; and for current day’s BUN, 19 ± 10 vs. 20 ± 11, p = 0.411, respectively.
IQ: interquartile range; SD: standard deviation; stan diff: standardized difference.