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. 2021 Feb 17;9:23. doi: 10.1186/s40337-021-00372-1

Table 4.

Neural responses to food stimuli in people with BN

BN participants HC participants Stimuli BN > HC BN < HC
Uher et al. 2004 [50] 10 19

Colour pictures of food > Non-food images

Emotional aversive > neutral images

ACC, MOFC L lateral and anterior parietal, LI parietal, L occipital, posterior cerebellum
Schienle et al. 2009 [56] 14 38 High calorie food images > disgust inducing images> neutral images Insula and ACC n/a
Brooks et al. 2011 [49] 8 24 Food > non-food DLPFC, postcentral gyrus, caudate, precentral gyrus, supplementary motor area bilateral superior temporal gyrus, bilateral insula, and visual cortex
Spangler et al. 2011 [59] 12 12

Computer generated thin and large body image

Scrambled image

Pregenual ACC n/a
Kim et al. 2012 [51] 20 20 High calorie food images > non-food images Anterior Insula, R middle frontal gyrus and cerebellum n/a
Skunde et al. 2016 [57] 28 29 Visual food stimuli > household item stimuli No differences seen No differences seen

R right, L left, DLPFC dorsolateral prefrontal cortex, OFC orbitofrontal cortex, ACC anterior cingulate cortex, M medial, I inferior