Table 1:
Paediatric AVR (N = 106) | All DAH (N = 259) | |
---|---|---|
Implantation period (years) | 2008–2019 | 2008–2019 |
Age at implantation, median (IQR) | 10.1 (4.8) | 21.3 (11.6–43.8) |
Follow-up, median (IQR) | 3.40 (1.8–4.9) | 2.5 (1.5–4.4) |
Total follow-up | 350 | 713 |
Sex (male), n (%) | 77 (73) | 176 (68) |
Number of previous operations | ||
0 | 46 | 145 |
1 | 34 | 69 |
2 | 15 | 29 |
>2 | 11 | 16 |
Type of previous procedures | ||
1 × AVR | 11 | 32 |
2 × AVR | 2 | 7 |
3 × AVR | 1 | 1 |
Catheter-based intervention | 40 | 48 |
Aortic valve repair | 15 | 23 |
Mean allograft diameter (mm), median (IQR) | 21 (19–23) | 23 (21–25) |
10–18 | 19 | 19 |
19–22 | 56 | 98 |
23–29 | 31 | 142 |
Implantation time (min), median (IQR) | ||
Total operation | 370 (311–466) | 324 (245–423) |
Cardiopulmonary bypass | 228 (191–289) | 174 (130–240) |
Cross-clamp | 145 (124–181) | 127 (99–158) |
Latest echocardiography | ||
Aortic annulus (mm), mean (SD) | 20.5 (3.8) | 22.0 (4.0) |
Aortic annulus, z-score, mean (SD) | −0.01 (1.49) | 0.18 (1.49) |
Effective orifice area (cm2), mean (SD) | 2.4 (0.8) | 2.9 (0.8) |
Peak gradient (mmHg), median (IQR) | 12 (8–21) | 11 (7–17) |
Regurgitation (grade 0–3), median (IQR) | 0.5 (0–1) | 0.5 (0–1) |
LV ejection fraction (%), mean (SD) | 62.3 (9.1) | 62.7 (8.4) |
Mean and SD are for normally distributed factors and median and IQR are for factors with no normal distribution.
AVR: aortic valve replacement; DAH: decellularized aortic homografts; IQR: interquartile range; LV: left ventricular; SD: standard deviation.