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. 2021 Feb 17;40:72. doi: 10.1186/s13046-021-01868-z

Table 1.

Association between MAPKAPK5-AS1 expression and clinicopathologic features of hepatocellular carcinoma patients

Characteristics n = 97 MAPKAPK5-AS1 levels p-value
High (n = 49) Low (n = 48)
Age (years) 0.774
  ≥ 60 64 33 31
  < 60 33 16 17
Gender 0.255
 Male 81 43 38
 Female 16 6 10
HBV infection 0.184
 Negative 19 7 12
 Positive 78 42 36
Liver cirrhosis 0.240
 Absent 29 12 17
 Present 68 37 31
AFP (ng/ml) 0.305
  ≤ 20 22 9 13
  > 20 75 40 35
Tumor size 0.006*
  ≤ 5 cm 41 14 27
  > 5 cm 56 35 21
Tumor multiplicity 0.001*
 Single 72 29 43
 Multiple 25 20 5
Vascular invasion 0.008*
 No 60 24 36
 Yes 37 25 12
TNM stage 0.001*
 I + II 78 33 45
 III + IV 19 16 3

* indicates statistically significant