Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 4;8:602047. doi: 10.3389/fped.2020.602047

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2021 Holgersen, Gao, Narayanan, Gaur, Carey, Barton, Pan, Muk, Thymann and Sangild.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Intestinal lesions and structure. (A) Incidence of severe NEC (defined as score ≥4 in at least one gut region) in rhIGF-1/BP-3 and control preterm pigs (n = 24). (B) NEC severity score across gut regions in rhIGF-1/BP-3 and control preterm pigs (n = 24). (C) Individual NEC scores in stomach, small intestine regions (highest score of the proximal, middle and distal section) and colon regions (highest score of the colon and cecum). (D) Villus length, crypt depth and Ki67 stained area relative to total nuclei area in tunica mucosa in mid small intestine (n = 23). Values are mean±SEM. (E) Immunohistochemically staining for Ki67 with hematoxylin counterstain in a representative middle small intestine section from a preterm pig treated with rhIGF-1/BP-3 and a control preterm pig. Pictures are 10x. *p < 0.05, **p < 0.01, ***p < 0.001.