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. Author manuscript; available in PMC: 2021 Feb 18.
Published in final edited form as: N Engl J Med. 2019 Aug 22;381(8):705–715. doi: 10.1056/NEJMoa1817364

Table 2.

Percentage Change in All-Cause Mortality in Association with an Increase of 10 μg per Cubic Meter in the 2-Day Moving Average Concentrations of PM10 and PM2.5, with and without Adjustment for Copollutants.*

Models PM10 PM2.5
Cities with Available Data Pooled Estimate P Value for Difference Cities with Available Data Pooled Estimate P Value for Difference
no. % (95% CI) no. % (95% CI)
PM and ozone 559 0.90 487 0.75
 Single-pollutant model of PM 0.43 (0.37–0.48) 0.68 (0.58–0.77)
 Two-pollutant model of PM with adjustment for ozone 0.43 (0.37–0.49) 0.66 (0.56–0.77)
PM and nitrogen dioxide 495 <0.001 466 <0.001
 Single-pollutant model of PM 0.43 (0.37–0.49) 0.66 (0.57–0.76)
 Two-pollutant model of PM with adjustment for nitrogen dioxide 0.28 (0.22–0.35) 0.42 (0.31–0.53)
PM and sulfur dioxide 495 0.007 466 0.007
 Single-pollutant model of PM 0.44 (0.38–0.50) 0.67 (0.57–0.76)
 Two-pollutant model of PM with adjustment for sulfur dioxide 0.36 (0.30–0.42) 0.52 (0.42–0.62)
PM and carbon monoxide 445 0.75 416 0.50
 Single-pollutant of PM 0.40 (0.34–0.46) 0.61 (0.51–0.71)
 Two-pollutant model of PM with adjustment for carbon monoxide 0.39 (0.32–0.46) 0.57 (0.46–0.68)
*

Pooled estimates are of the percentage change in daily all-cause mortality per 10-μg-cubic-meter increase in PM10 or PM2.5 concentration. The P value for difference was calculated by evaluating a binary variable (with and without the adjustment for the copollutant) in a paired z-test with estimates from both single-pollutant and two-pollutant models. A P value of less than 0.05 was considered to be statistically significant for the difference.