Day 4 |
Fever and flu-like illness for 3 days; spontaneous remission |
Day 0 |
Admission at emergency department with low blood pressure, elevated serum lactate (2.7 mmol/L) and left ventricular dysfunction [left ventricular ejection fraction (LVEF) 25%]. Diagnosis of cardiogenic shock and referral to our unit |
Day 0 + 2 h |
Coronary angiography, implantation of ImpellaTM CP device, and right ventricular biopsy |
Day 0 + 4 h |
Increased central venous pressure and signs of right ventricular (RV) failure on echocardiography (decreased tricuspid annular plane systolic excursion, RV dilation, and D-shaping of interventricular septum) for which milrinone was initiated at 0.3 mcg/kg/min |
Day 2 |
Biopsy result: eosinophilic infiltration. Methylprednisone was started at 2 mg/kg/day. |
Day 3 |
Initiation of Ramipril at 2.5 mg/day, gradual increase in dose. |
Day 5 |
Partial recuperation of cardiac function on echocardiography. Successful weaning trial (30 min at minimal flow level) of ImpellaTM followed by device removal. |
Day 7 |
Further uptitration of Ramipril to 5 mg/day and further clinical improvement. Intensive care unit discharge. |
Day 14 |
Normalized LVEF (52%) on cardiac magnetic resonance imaging. |
Day 16 |
Discharge from hospital; still on Ramipril 5 mg/day and methylprednisone 24 mg/day. |
4 months |
Stop of methylprednisone. Stable (normalized) cardiac function on echocardiography. |