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. 2020 Dec 7;4(6):1–5. doi: 10.1093/ehjcr/ytaa444
Day 4 Fever and flu-like illness for 3 days; spontaneous remission
Day 0 Admission at emergency department with low blood pressure, elevated serum lactate (2.7 mmol/L) and left ventricular dysfunction [left ventricular ejection fraction (LVEF) 25%]. Diagnosis of cardiogenic shock and referral to our unit
Day 0 + 2 h Coronary angiography, implantation of ImpellaTM CP device, and right ventricular biopsy
Day 0 + 4 h Increased central venous pressure and signs of right ventricular (RV) failure on echocardiography (decreased tricuspid annular plane systolic excursion, RV dilation, and D-shaping of interventricular septum) for which milrinone was initiated at 0.3 mcg/kg/min
Day 2 Biopsy result: eosinophilic infiltration. Methylprednisone was started at 2 mg/kg/day.
Day 3 Initiation of Ramipril at 2.5 mg/day, gradual increase in dose.
Day 5 Partial recuperation of cardiac function on echocardiography. Successful weaning trial (30 min at minimal flow level) of ImpellaTM followed by device removal.
Day 7 Further uptitration of Ramipril to 5 mg/day and further clinical improvement. Intensive care unit discharge.
Day 14 Normalized LVEF (52%) on cardiac magnetic resonance imaging.
Day 16 Discharge from hospital; still on Ramipril 5 mg/day and methylprednisone 24 mg/day.
4 months Stop of methylprednisone. Stable (normalized) cardiac function on echocardiography.