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. 2020 Aug 9;22(12):2258–2268. doi: 10.1002/ejhf.1945

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© 2020 The Authors. European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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EJHF-1945-FIG-0004-c — Prognostic impacts of temporal changes in left ventricular (LV) structures in patients with heart failure and preserved ejection fraction (HFpEF). The upper panel shows dynamic LV structural changes in HFpEF patients; temporal LV structural changes occur bidirectionally in terms of the progression/regression of LV hypertrophy (LVH) and enlargement (LVE). The middle panel shows the incidence rates per 1000 person‐years for the primary outcome after 1‐year changes in LV structures. The lower panel shows the subsequent risk for the primary outcome after 1‐year changes in LV structures in the univariable Cox proportional hazard model. CI, confidence interval; HR, hazard ratio.