| Evidence‐based recommendation (2.6) |
|---|
| We recommend not to use local administration of statin gels (atorvastatin, simvastatin, rosuvastatin) as adjuncts to subgingival instrumentation. |
| Supporting literature Donos et al. (2019) |
| Quality of evidence Twelve placebo‐controlled RCTs (n = 753), for 1.2% atorvastatin (six RCTs, n = 180), 1.2% simvastatin gel (5 RCTs, n = 118) and 1.2% rosuvastatin gel (four RCTs, n = 122) |
| Grade of recommendation Grade A—↓↓ |
| Strength of consensus Strong consensus (0% of the group abstained due to potential CoI) |
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