Evidence‐based recommendation (2.8)
We suggest not to use systemic sub‐antimicrobial dose doxycycline (SDD) as an adjunct to subgingival instrumentation.
Supporting literature Donos et al. (2019)
Quality of evidence Eight placebo‐controlled RCTs (14 publications, n = 610). Meta‐analysis on PPD reduction was performed in five RCTs (n = 484)
Grade of recommendation Grade B—↓
Strength of consensus Consensus (1.3% of the group abstained due to potential CoI)